Trade Name:

AC Hexapeptide 1 PF

INCI Name:

Water & Hexapeptide-11

 Supplier: Active Concepts


Applications :

Collagen Synthesis, Increase Tone

Benefits :

Hexapeptides are 6 amino acid sequence peptides that have been used in personal care and cosmetics to increase collagen synthesis for improved tone while also reducing the appearance of fine lines and wrinkles. Peptide technology is useful in cosmetic and personal care products as they may penetrate the skin and bind to cell surface receptors to stimulate cell activity. Saccharomyces cerevisiae is cultured in an amino acid rich environment; following fermentation AC Hexapeptide 1 PF is isolated using various filtration techniques. AC Hexapeptide 1 PF may be useful for a variety of anti-aging benefits such as increasing skin tone and elasticity and may also improve skin hydration. Efficacy testing indicates that AC Hexapeptide 1 PF may also increase ATP synthesis. Overall cellular efficiency may be increased by improving the cell’s ATP levels.

Other :

.: Background :.

Saccharomyces cerevisiae is considered to be a primitive single celled organism, yet it seems to have evolved a series of mechanisms to protect itself from stressfulsituations such as extreme temperature conditions and oxidative stress. In factSaccharomyces is capable of employing a series of mechanisms as a response to cold-shock that stimulate the accumulation of trehalose, glycerol and heat shock protein in the organism. These components have been shown to induce changes in the cell, which increase membrane fluidity as a primary response to cold shock. The high-osmolarity glycerol mitogenactivated protein kinase pathway and MSn2/4p are classical stress responses employed by Saccharomyces as a means of protecting the organism from temperature shock and oxidative stress. Isolates from yeast such as heat shock proteins, have been used for their anti-irritantand wound healing benefits, and they have also been shown to increase intracellularrespiration, improve intracellular metabolism while also increasing collagen andelastin production. Originally touted as a means to mask signs of sleep deprivation by reducing under eye puffiness, yeast extracts have now also been employed to improve skin tone and elasticity as well as increase stratum corneum hydration and cellular renewal. Live Yeast Cell Derivatives (LYCD) have also been used to increase oxygen consumption, therefore limiting the oxygen that is available to becomereactive oxygen species (ROS).

.: Formulation :.

Soluble / Miscible: : Water Soluble
Recommended use level: 0.5 – 3.0%

 .: Additional Information :.


Natural Antimicrobial: Leuconostoc/Radish Root Ferment Filtrate
Preservatives: None
Antioxidants: None
Other additives: None